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SPRAVATO

In-office treatment for depression that has not responded to antidepressants.

SPRAVATO is an FDA-approved esketamine nasal spray for treatment-resistant depression. Every session happens in our Acton office under clinical supervision.

How SPRAVATO works

Esketamine works on the brain's glutamate system — a different mechanism from standard antidepressants, which is why it can help when they haven't. It is FDA-approved for treatment-resistant depression and is always taken alongside an oral antidepressant.

Each session happens in our office: you self-administer the nasal spray under clinical supervision, then remain with us for a monitoring period before heading home with a driver. We handle the insurance enrollment and authorization the program requires.

A woman holding a SPRAVATO nasal spray device just below her nose.
At a glance
Location
Acton, MA
Setting
In-office · supervised
Monitoring
Required after each dose
Pairing
Taken with an oral antidepressant

Questions about SPRAVATO

Start with the intake form.

Tell us what you're looking for, preferred visit type, and insurance. We review each request and follow up within 1-2 business days.

Sunlight through the open front door of Three Rivers Mental Health.